A Protective Effect of Pirfenidone in Lung Fibroblast–Endothelial Cell Network via Inhibition of Rho-Kinase Activity

Pulmonary fibrosis is a life-threatening disease that has been attributed to several causes. Specifically, vascular injury is thought to be involved in the pathogenesis of fibrosis. The effects of the antifibrotic drug pirfenidone on angiogenesis have not been fully elucidated. This study aimed to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Yusuke, Shimizu, Yasuo, Fujimaki-Shiraishi, Mio, Uchida, Nobuhiko, Takemasa, Akihiro, Niho, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452915/
https://www.ncbi.nlm.nih.gov/pubmed/37626755
http://dx.doi.org/10.3390/biomedicines11082259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452915/
https://www.ncbi.nlm.nih.gov/pubmed/37626755
http://dx.doi.org/10.3390/biomedicines11082259

Ejemplares similares