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A Protective Effect of Pirfenidone in Lung Fibroblast–Endothelial Cell Network via Inhibition of Rho-Kinase Activity
Pulmonary fibrosis is a life-threatening disease that has been attributed to several causes. Specifically, vascular injury is thought to be involved in the pathogenesis of fibrosis. The effects of the antifibrotic drug pirfenidone on angiogenesis have not been fully elucidated. This study aimed to i...
Autores principales: | Nakamura, Yusuke, Shimizu, Yasuo, Fujimaki-Shiraishi, Mio, Uchida, Nobuhiko, Takemasa, Akihiro, Niho, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452915/ https://www.ncbi.nlm.nih.gov/pubmed/37626755 http://dx.doi.org/10.3390/biomedicines11082259 |
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