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Metabolic Disruption Induced by mTOR Signaling Pathway Inhibition in Regulatory T-Cell Expansion for Clinical Application

Background: Regulatory T cell (Treg) therapy is considered an alternative approach to induce tolerance in transplantation. If successful, this therapy may have implications on immunosuppression minimization/withdrawal to reduce drug-induced toxicity in patients. The aim of this study was to assess t...

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Detalles Bibliográficos
Autores principales: Gedaly, Roberto, Orozco, Gabriel, Ancheta, Alexandre P., Donoho, Mackenzie, Desai, Siddharth N., Chapelin, Fanny, Khurana, Aman, Lewis, Lillie J., Zhang, Cuiping, Marti, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453008/
https://www.ncbi.nlm.nih.gov/pubmed/37626877
http://dx.doi.org/10.3390/cells12162066