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Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription

SIMPLE SUMMARY: Colorectal cancer (CRC) is the leading cause of cancer-related death worldwide, and new therapeutic approaches are direly needed to improve the outcomes of metastatic disease. Herein, we uncover that menin, a nuclear scaffold protein that has a myriad of tissue-specific effects on ge...

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Detalles Bibliográficos
Autores principales: Nyul, Thomas E., Beyries, Keely, Hojnacki, Taylor, Glynn, Rebecca, Paulosky, Kayla E., Gedela, Anitej, Majer, Ariana, Altman, Lily, Buckley, Kole H., Feng, Zijie, Sun, Kunfeng, Peng, Zhicheng, Tobias, John W., Hua, Xianxin, Katona, Bryson W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453013/
https://www.ncbi.nlm.nih.gov/pubmed/37627154
http://dx.doi.org/10.3390/cancers15164126