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Variable Cre Recombination Efficiency in Placentas of Cyp19-Cre ROSA(mT/mG) Transgenic Mice

The aromatase-Cre recombinase (Cyp19-Cre) transgenic mouse model has been extensively used for placenta-specific gene inactivation. In a pilot study, we observed unexpected phenotypes using this mouse strain, which prompted an extensive characterization of Cyp19-Cre placental phenotypes using ROSA(m...

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Detalles Bibliográficos
Autores principales: Anamthathmakula, Prashanth, Shallie, Philemon D., Nayak, Neha, Dhal, Sabita, Vivian, Jay L., Mor, Gil, Soares, Michael J., Nayak, Nihar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453067/
https://www.ncbi.nlm.nih.gov/pubmed/37626906
http://dx.doi.org/10.3390/cells12162096