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Understanding DNA Damage Response and DNA Repair in Multiple Myeloma

SIMPLE SUMMARY: Multiple myeloma (MM), a malignant plasma cell disorder, is characterized by abnormal DNA damage response (DDR). MM cells adapt over time via gene mutations or chromosomal aberrations, including changes to DDR and DNA repair genes. Increased DNA repair and avoidance of DNA-damaged in...

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Detalles Bibliográficos
Autores principales: Petrilla, Cole, Galloway, Joshua, Kudalkar, Ruchi, Ismael, Aya, Cottini, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453069/
https://www.ncbi.nlm.nih.gov/pubmed/37627183
http://dx.doi.org/10.3390/cancers15164155