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Ubiquitin Engineering for Interrogating the Ubiquitin–Proteasome System and Novel Therapeutic Strategies

Protein turnover, a highly regulated process governed by the ubiquitin–proteasome system (UPS), is essential for maintaining cellular homeostasis. Dysregulation of the UPS has been implicated in various diseases, including viral infections and cancer, making the proteins in the UPS attractive target...

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Detalles Bibliográficos
Autores principales: Tang, Jason Q., Marchand, Mary M., Veggiani, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453149/
https://www.ncbi.nlm.nih.gov/pubmed/37626927
http://dx.doi.org/10.3390/cells12162117