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Glucocorticoid Receptor Regulates and Interacts with LEDGF/p75 to Promote Docetaxel Resistance in Prostate Cancer Cells

Patients with advanced prostate cancer (PCa) invariably develop resistance to anti-androgen therapy and taxane-based chemotherapy. Glucocorticoid receptor (GR) has been implicated in PCa therapy resistance; however, the mechanisms underlying GR-mediated chemoresistance remain unclear. Lens epitheliu...

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Detalles Bibliográficos
Autores principales: Sanchez-Hernandez, Evelyn S., Ochoa, Pedro T., Suzuki, Tise, Ortiz-Hernandez, Greisha L., Unternaehrer, Juli J., Alkashgari, Hossam R., Diaz Osterman, Carlos J., Martinez, Shannalee R., Chen, Zhong, Kremsky, Isaac, Wang, Charles, Casiano, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453226/
https://www.ncbi.nlm.nih.gov/pubmed/37626856
http://dx.doi.org/10.3390/cells12162046