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Neuronal atg1 Coordinates Autophagy Induction and Physiological Adaptations to Balance mTORC1 Signalling

The mTORC1 nutrient-sensing pathway integrates metabolic and endocrine signals into the brain to evoke physiological responses to food deprivation, such as autophagy. Nevertheless, the impact of neuronal mTORC1 activity on neuronal circuits and organismal metabolism remains obscure. Here, we show th...

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Detalles Bibliográficos
Autores principales: Metaxakis, Athanasios, Pavlidis, Michail, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453232/
https://www.ncbi.nlm.nih.gov/pubmed/37626835
http://dx.doi.org/10.3390/cells12162024