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Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH

BACKGROUND: Hematoma clearance has been a proposed therapeutic strategy for hemorrhagic stroke. This study investigated the impact of CX3CR1 (CX3C chemokine receptor 1) activation mediated by r-FKN (recombinant fractalkine) on hematoma resolution, neuroinflammation, and the underlying mechanisms inv...

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Detalles Bibliográficos
Autores principales: Chen, Xionghui, He, Xuying, Xu, Feng, Xu, Ningbo, Sharifi, Nona Hashem, Zhang, Pengjie, Flores, Jerry J., Wu, Lei, He, Qiuguang, Kanamaru, Hideki, Zhu, Shiyi, Dong, Siyuan, Han, Mingyang, Yuan, Ye, Huang, Lei, Miao, Liyan, Zhang, John H., Zhou, Youxin, Tang, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453335/
https://www.ncbi.nlm.nih.gov/pubmed/37465997
http://dx.doi.org/10.1161/STROKEAHA.123.043005