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Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH
BACKGROUND: Hematoma clearance has been a proposed therapeutic strategy for hemorrhagic stroke. This study investigated the impact of CX3CR1 (CX3C chemokine receptor 1) activation mediated by r-FKN (recombinant fractalkine) on hematoma resolution, neuroinflammation, and the underlying mechanisms inv...
Autores principales: | Chen, Xionghui, He, Xuying, Xu, Feng, Xu, Ningbo, Sharifi, Nona Hashem, Zhang, Pengjie, Flores, Jerry J., Wu, Lei, He, Qiuguang, Kanamaru, Hideki, Zhu, Shiyi, Dong, Siyuan, Han, Mingyang, Yuan, Ye, Huang, Lei, Miao, Liyan, Zhang, John H., Zhou, Youxin, Tang, Jiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453335/ https://www.ncbi.nlm.nih.gov/pubmed/37465997 http://dx.doi.org/10.1161/STROKEAHA.123.043005 |
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