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PM(2.5)-Induced Cardiac Structural Modifications and Declined Pro-Survival Signalling Pathways Are Responsible for the Inefficiency of GSK-3β Inhibitor in Attenuating Myocardial Ischemia-Reperfusion Injury in Rats

Circulatory GSK3β is recognized as a biomarker and therapeutic target for diseases, including myocardial diseases. However, its potential as a target for myocardial ischemia-reperfusion injury (IR) in the presence of PM(2.5) exposure is unclear. Wistar rats underwent IR following either a 21-day or...

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Detalles Bibliográficos
Autores principales: Sivakumar, Bhavana, Ali, Nemat, Ahmad, Sheikh F., Nadeem, Ahmed, Waseem, Mohammad, Kurian, Gino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453520/
https://www.ncbi.nlm.nih.gov/pubmed/37626874
http://dx.doi.org/10.3390/cells12162064