Cargando…
PM(2.5)-Induced Cardiac Structural Modifications and Declined Pro-Survival Signalling Pathways Are Responsible for the Inefficiency of GSK-3β Inhibitor in Attenuating Myocardial Ischemia-Reperfusion Injury in Rats
Circulatory GSK3β is recognized as a biomarker and therapeutic target for diseases, including myocardial diseases. However, its potential as a target for myocardial ischemia-reperfusion injury (IR) in the presence of PM(2.5) exposure is unclear. Wistar rats underwent IR following either a 21-day or...
Autores principales: | Sivakumar, Bhavana, Ali, Nemat, Ahmad, Sheikh F., Nadeem, Ahmed, Waseem, Mohammad, Kurian, Gino A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453520/ https://www.ncbi.nlm.nih.gov/pubmed/37626874 http://dx.doi.org/10.3390/cells12162064 |
Ejemplares similares
-
PM(2.5) Exposure-Linked Mitochondrial Dysfunction Negates SB216763-Mediated Cardio-Protection against Myocardial Ischemia–Reperfusion Injury
por: Sivakumar, Bhavana, et al.
Publicado: (2023) -
Consequential Impact of Particulate Matter Linked Inter-Fibrillar Mitochondrial Dysfunction in Rat Myocardium Subjected to Ischemia Reperfusion Injury
por: Sivakumar, Bhavana, et al.
Publicado: (2022) -
Fisetin Attenuates Myocardial Ischemia-Reperfusion Injury by Activating the Reperfusion Injury Salvage Kinase (RISK) Signaling Pathway
por: Shanmugam, Karthi, et al.
Publicado: (2021) -
Diabetic Hearts Exhibit Global DNA Hypermethylation That Alter the Mitochondrial Functional Genes to Enhance the Sensitivity of the Heart to Ischemia Reperfusion Injury
por: Boovarahan, Sri Rahavi, et al.
Publicado: (2022) -
Age-associated global DNA hypermethylation augments the sensitivity of hearts towards ischemia-reperfusion injury
por: Boovarahan, Sri Rahavi, et al.
Publicado: (2022)