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Development of Beta-Amyloid-Specific CAR-Tregs for the Treatment of Alzheimer’s Disease

Background: Alzheimer’s disease (AD) is a neurodegenerative disease that remains uncured. Its pathogenesis is characterized by the formation of β-amyloid (Aβ) plaques. The use of antigen-specific regulatory T cells (Tregs) through adoptive transfer has shown promise for the treatment of many inflamm...

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Detalles Bibliográficos
Autores principales: Saetzler, Valerie, Riet, Tobias, Schienke, Andrea, Henschel, Pierre, Freitag, Kiara, Haake, Alexander, Heppner, Frank L., Buitrago-Molina, Laura Elisa, Noyan, Fatih, Jaeckel, Elmar, Hardtke-Wolenski, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453937/
https://www.ncbi.nlm.nih.gov/pubmed/37626926
http://dx.doi.org/10.3390/cells12162115