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Development of Beta-Amyloid-Specific CAR-Tregs for the Treatment of Alzheimer’s Disease
Background: Alzheimer’s disease (AD) is a neurodegenerative disease that remains uncured. Its pathogenesis is characterized by the formation of β-amyloid (Aβ) plaques. The use of antigen-specific regulatory T cells (Tregs) through adoptive transfer has shown promise for the treatment of many inflamm...
Autores principales: | Saetzler, Valerie, Riet, Tobias, Schienke, Andrea, Henschel, Pierre, Freitag, Kiara, Haake, Alexander, Heppner, Frank L., Buitrago-Molina, Laura Elisa, Noyan, Fatih, Jaeckel, Elmar, Hardtke-Wolenski, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453937/ https://www.ncbi.nlm.nih.gov/pubmed/37626926 http://dx.doi.org/10.3390/cells12162115 |
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