Cargando…

The NMR studies of CMP inhibition of polysialylation

The overexpression of polysialic acid (polySia) on neural cell adhesion molecules (NCAM) promotes hypersialylation, and thus benefits cancer cell migration and invasion. It has been proposed that the binding between the polysialyltransferase domain (PSTD) and CMP-Sia needs to be inhibited in order t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Bo, Liao, Si-Ming, Liu, Xue-Hui, Liang, Shi-Jie, Huang, Jun, Lin, Mei, Meng, Li, Wang, Qing-Yan, Huang, Ri-Bo, Zhou, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453990/
https://www.ncbi.nlm.nih.gov/pubmed/37615033
http://dx.doi.org/10.1080/14756366.2023.2248411