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Hedgehog-Related Mutation Causes Bone Malformations with or without Hereditary Gene Mutations
The hedgehog (Hh) family consists of numerous signaling mediators that play important roles at various stages of development. Thus, the Hh pathway is essential for bone tissue development and tumorigenesis. Gorlin syndrome is a skeletal and tumorigenic disorder caused by gain-of-function mutations i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454035/ https://www.ncbi.nlm.nih.gov/pubmed/37629084 http://dx.doi.org/10.3390/ijms241612903 |