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A Model of iPSC-Derived Macrophages with TNFAIP3 Overexpression Reveals the Peculiarities of TNFAIP3 Protein Expression and Function in Human Macrophages

Macrophages play a crucial role in the development and control of inflammation. Understanding the mechanisms balancing macrophage inflammatory activity is important to develop new strategies for treating inflammation-related diseases. TNF-α-induced protein 3 (TNFAIP3, A20) is a negative regulator of...

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Detalles Bibliográficos
Autores principales: Sheveleva, Olga, Protasova, Elena, Nenasheva, Tatiana, Butorina, Nina, Melnikova, Victoria, Gerasimova, Tatiana, Sakovnich, Olga, Kurinov, Alexander, Grigor’eva, Elena, Medvedev, Sergey, Lyadova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454046/
https://www.ncbi.nlm.nih.gov/pubmed/37629049
http://dx.doi.org/10.3390/ijms241612868