The ε-Isozyme of Protein Kinase C (PKCε) Is Impaired in ALS Motor Cortex and Its Pulse Activation by Bryostatin-1 Produces Long Term Survival in Degenerating SOD1-G93A Motor Neuron-like Cells

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, characterized by a progressive depletion of upper and lower motor neurons (MNs) in the brain and spinal cord. The aberrant regulation of several PKC-mediated signal transduction pathways in A...

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Detalles Bibliográficos
Autores principales: La Cognata, Valentina, D’Amico, Agata Grazia, Maugeri, Grazia, Morello, Giovanna, Guarnaccia, Maria, Magrì, Benedetta, Aronica, Eleonora, Alkon, Daniel L., D’Agata, Velia, Cavallaro, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454105/
https://www.ncbi.nlm.nih.gov/pubmed/37629005
http://dx.doi.org/10.3390/ijms241612825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454105/
https://www.ncbi.nlm.nih.gov/pubmed/37629005
http://dx.doi.org/10.3390/ijms241612825

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