Pharmacology and Rationale for Seralutinib in the Treatment of Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a complex disorder characterized by vascular remodeling and a consequent increase in pulmonary vascular resistance. The histologic hallmarks of PAH include plexiform and neointimal lesions of the pulmonary arterioles, which are composed of dysregulated, apopt...

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Detalles Bibliográficos
Autores principales: Pullamsetti, Soni Savai, Sitapara, Ravikumar, Osterhout, Robin, Weiss, Astrid, Carter, Laura L., Zisman, Lawrence S., Schermuly, Ralph Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454154/
https://www.ncbi.nlm.nih.gov/pubmed/37628831
http://dx.doi.org/10.3390/ijms241612653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454154/
https://www.ncbi.nlm.nih.gov/pubmed/37628831
http://dx.doi.org/10.3390/ijms241612653

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