Inhibition of the Exocyst Complex Attenuates the LRRK2 Pathological Effects

Pathological mutations in leucine-rich repeat kinase 2 (LRRK2) gene are the major genetic cause of Parkinson’s disease (PD). Multiple lines of evidence link LRRK2 to the control of vesicle dynamics through phosphorylation of a subset of RAB proteins. However, the molecular mechanisms underlying thes...

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Detalles Bibliográficos
Autores principales: Ciampelli, Cristina, Galleri, Grazia, Puggioni, Silvia, Fais, Milena, Iannotta, Lucia, Galioto, Manuela, Becciu, Marta, Greggio, Elisa, Bernardoni, Roberto, Crosio, Claudia, Iaccarino, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454163/
https://www.ncbi.nlm.nih.gov/pubmed/37628835
http://dx.doi.org/10.3390/ijms241612656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454163/
https://www.ncbi.nlm.nih.gov/pubmed/37628835
http://dx.doi.org/10.3390/ijms241612656

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