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Inhibition of the Exocyst Complex Attenuates the LRRK2 Pathological Effects

Pathological mutations in leucine-rich repeat kinase 2 (LRRK2) gene are the major genetic cause of Parkinson’s disease (PD). Multiple lines of evidence link LRRK2 to the control of vesicle dynamics through phosphorylation of a subset of RAB proteins. However, the molecular mechanisms underlying thes...

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Detalles Bibliográficos
Autores principales:	Ciampelli, Cristina, Galleri, Grazia, Puggioni, Silvia, Fais, Milena, Iannotta, Lucia, Galioto, Manuela, Becciu, Marta, Greggio, Elisa, Bernardoni, Roberto, Crosio, Claudia, Iaccarino, Ciro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454163/ https://www.ncbi.nlm.nih.gov/pubmed/37628835 http://dx.doi.org/10.3390/ijms241612656

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