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The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test

(1) Background: This paper aims to assess the existence of significant differences between two dietary regimes (omnivorous vs. semi-vegetarian) with reference to some oxidative stress markers (SOD, GPx, TRxR, GR, AGEs, and AOPPs) using non-parametric combination methodology based on a permutation te...

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Autores principales: Zirilli, Agata, Ruggeri, Rosaria Maddalena, Barbalace, Maria Cristina, Hrelia, Silvana, Giovanella, Luca, Campennì, Alfredo, Cannavò, Salvatore, Alibrandi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454221/
https://www.ncbi.nlm.nih.gov/pubmed/37628461
http://dx.doi.org/10.3390/healthcare11162263
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author Zirilli, Agata
Ruggeri, Rosaria Maddalena
Barbalace, Maria Cristina
Hrelia, Silvana
Giovanella, Luca
Campennì, Alfredo
Cannavò, Salvatore
Alibrandi, Angela
author_facet Zirilli, Agata
Ruggeri, Rosaria Maddalena
Barbalace, Maria Cristina
Hrelia, Silvana
Giovanella, Luca
Campennì, Alfredo
Cannavò, Salvatore
Alibrandi, Angela
author_sort Zirilli, Agata
collection PubMed
description (1) Background: This paper aims to assess the existence of significant differences between two dietary regimes (omnivorous vs. semi-vegetarian) with reference to some oxidative stress markers (SOD, GPx, TRxR, GR, AGEs, and AOPPs) using non-parametric combination methodology based on a permutation test. (2) Methods: At the endocrinology unit of Messina University Hospital, two hundred subjects were asked to fill out a questionnaire about their dietary habits. None were under any pharmacological treatment. Using the NPC test, all comparisons were performed stratifying patients according to gender, age (≤40 or >40 years), BMI (normal weight vs. overweight), physical activity (sedentary vs. active lifestyle), TSH, FT4 levels in quartiles, and diagnosis of Hashimoto’s thyroiditis. We evaluated differences in oxidative stress parameters in relation to two examined dietary regimes (omnivorous vs. semi-vegetarian). (3) Results: The antioxidant parameters GPx and TRxR were significantly lower in subjects with an omnivorous diet than in semi-vegetarians, particularly in females, both age groups, subjects with normal weight, those not affected by Hashimoto’s thyroiditis, and both the sedentary and active lifestyle groups. Finally, the AGE and AOPP markers were significantly lower in semi-vegetarians. (4) Conclusion: Thanks to the NPC methodology, we can state that dietary patterns exert a significant influence on some oxidative stress parameters.
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spelling pubmed-104542212023-08-26 The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test Zirilli, Agata Ruggeri, Rosaria Maddalena Barbalace, Maria Cristina Hrelia, Silvana Giovanella, Luca Campennì, Alfredo Cannavò, Salvatore Alibrandi, Angela Healthcare (Basel) Article (1) Background: This paper aims to assess the existence of significant differences between two dietary regimes (omnivorous vs. semi-vegetarian) with reference to some oxidative stress markers (SOD, GPx, TRxR, GR, AGEs, and AOPPs) using non-parametric combination methodology based on a permutation test. (2) Methods: At the endocrinology unit of Messina University Hospital, two hundred subjects were asked to fill out a questionnaire about their dietary habits. None were under any pharmacological treatment. Using the NPC test, all comparisons were performed stratifying patients according to gender, age (≤40 or >40 years), BMI (normal weight vs. overweight), physical activity (sedentary vs. active lifestyle), TSH, FT4 levels in quartiles, and diagnosis of Hashimoto’s thyroiditis. We evaluated differences in oxidative stress parameters in relation to two examined dietary regimes (omnivorous vs. semi-vegetarian). (3) Results: The antioxidant parameters GPx and TRxR were significantly lower in subjects with an omnivorous diet than in semi-vegetarians, particularly in females, both age groups, subjects with normal weight, those not affected by Hashimoto’s thyroiditis, and both the sedentary and active lifestyle groups. Finally, the AGE and AOPP markers were significantly lower in semi-vegetarians. (4) Conclusion: Thanks to the NPC methodology, we can state that dietary patterns exert a significant influence on some oxidative stress parameters. MDPI 2023-08-11 /pmc/articles/PMC10454221/ /pubmed/37628461 http://dx.doi.org/10.3390/healthcare11162263 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zirilli, Agata
Ruggeri, Rosaria Maddalena
Barbalace, Maria Cristina
Hrelia, Silvana
Giovanella, Luca
Campennì, Alfredo
Cannavò, Salvatore
Alibrandi, Angela
The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test
title The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test
title_full The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test
title_fullStr The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test
title_full_unstemmed The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test
title_short The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test
title_sort influence of food regimes on oxidative stress: a permutation-based approach using the npc test
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454221/
https://www.ncbi.nlm.nih.gov/pubmed/37628461
http://dx.doi.org/10.3390/healthcare11162263
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