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Production, Exacerbating Effect, and EV-Mediated Transcription of Hepatic CCN2 in NASH: Implications for Diagnosis and Therapy of NASH Fibrosis

Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, hepatocyte ballooning, and inflammation and may progress to include increasingly severe fibrosis, which portends more serious disease and is predictive of patient mortality. Diagnostic and therapeutic options for NASH fibrosis are l...

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Detalles Bibliográficos
Autores principales: Li, Xinlei, Chen, Ruju, Kemper, Sherri, Brigstock, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454308/
https://www.ncbi.nlm.nih.gov/pubmed/37629004
http://dx.doi.org/10.3390/ijms241612823