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KLF10 Inhibits TGF-β-Mediated Activation of Hepatic Stellate Cells via Suppression of ATF3 Expression

Liver fibrosis is a progressive and debilitating condition characterized by the excessive deposition of extracellular matrix proteins. Stellate cell activation, a major contributor to fibrogenesis, is influenced by Transforming growth factor (TGF-β)/SMAD signaling. Although Krüppel-like-factor (KLF)...

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Detalles Bibliográficos
Autores principales: Hwang, Soonjae, Park, Sangbin, Yaseen, Uzma, Lee, Ho-Jae, Cha, Ji-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454374/
https://www.ncbi.nlm.nih.gov/pubmed/37628783
http://dx.doi.org/10.3390/ijms241612602