Interferon Gamma Enhances Cytoprotective Pathways via Nrf2 and MnSOD Induction in Friedreich’s Ataxia Cells

Friedreich’s ataxia (FRDA) is a rare monogenic disease characterized by multisystem, slowly progressive degeneration. Because of the genetic defect in a non-coding region of FXN gene, FRDA cells exhibit severe deficit of frataxin protein levels. Hence, FRDA pathophysiology is characterized by a plet...

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Detalles Bibliográficos
Autores principales: Luffarelli, Riccardo, Panarello, Luca, Quatrana, Andrea, Tiano, Francesca, Fortuni, Silvia, Rufini, Alessandra, Malisan, Florence, Testi, Roberto, Condò, Ivano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454386/
https://www.ncbi.nlm.nih.gov/pubmed/37628866
http://dx.doi.org/10.3390/ijms241612687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454386/
https://www.ncbi.nlm.nih.gov/pubmed/37628866
http://dx.doi.org/10.3390/ijms241612687

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