Fusion of Hsp70 to GFP Impairs Its Function and Causes Formation of Misfolded Protein Deposits under Mild Stress in Yeast

Protein misfolding is a common feature of aging, various diseases and stresses. Recent work has revealed that misfolded proteins can be gathered into specific compartments, which can limit their deleterious effects. Chaperones play a central role in the formation of these misfolded protein deposits...

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Detalles Bibliográficos
Autores principales: Grosfeld, Erika V., Beizer, Anastasia Yu., Dergalev, Alexander A., Agaphonov, Michael O., Alexandrov, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454418/
https://www.ncbi.nlm.nih.gov/pubmed/37628938
http://dx.doi.org/10.3390/ijms241612758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454418/
https://www.ncbi.nlm.nih.gov/pubmed/37628938
http://dx.doi.org/10.3390/ijms241612758

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