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Fusion of Hsp70 to GFP Impairs Its Function and Causes Formation of Misfolded Protein Deposits under Mild Stress in Yeast
Protein misfolding is a common feature of aging, various diseases and stresses. Recent work has revealed that misfolded proteins can be gathered into specific compartments, which can limit their deleterious effects. Chaperones play a central role in the formation of these misfolded protein deposits...
Autores principales: | Grosfeld, Erika V., Beizer, Anastasia Yu., Dergalev, Alexander A., Agaphonov, Michael O., Alexandrov, Alexander I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454418/ https://www.ncbi.nlm.nih.gov/pubmed/37628938 http://dx.doi.org/10.3390/ijms241612758 |
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