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KRAS Mutation Status in Bulgarian Patients with Advanced and Metastatic Colorectal Cancer

RAS somatic variants are predictors of resistance to anti-EGFR therapy for colorectal cancer (CRC) and affect the outcome of the disease. Our study aimed to evaluate the frequency of RAS, with a focus on KRAS variants, and their association with tumor location and some clinicopathological characteri...

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Detalles Bibliográficos
Autores principales: Radanova, Maria, Mihaylova, Galya, Stoyanov, George St., Draganova, Vyara, Zlatarov, Aleksandar, Kolev, Nikola, Dimitrova, Eleonora, Conev, Nikolay, Ivanova, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454445/
https://www.ncbi.nlm.nih.gov/pubmed/37628934
http://dx.doi.org/10.3390/ijms241612753