Crystal Structure of the Catalytic Domain of a Botulinum Neurotoxin Homologue from Enterococcus faecium: Potential Insights into Substrate Recognition

Clostridium botulinum neurotoxins (BoNTs) are the most potent toxins known, causing the deadly disease botulism. They function through Zn(2+)-dependent endopeptidase cleavage of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins, preventing vesicular fusion and su...

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Detalles Bibliográficos
Autores principales: Gregory, Kyle S., Hall, Peter-Rory, Onuh, Jude Prince, Mojanaga, Otsile O., Liu, Sai Man, Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454453/
https://www.ncbi.nlm.nih.gov/pubmed/37628902
http://dx.doi.org/10.3390/ijms241612721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454453/
https://www.ncbi.nlm.nih.gov/pubmed/37628902
http://dx.doi.org/10.3390/ijms241612721

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