Enhancement of Neutralization Responses through Sequential Immunization of Stable Env Trimers Based on Consensus Sequences from Select Time Points by Mimicking Natural Infection

HIV-1 vaccines have been challenging to develop, partly due to the high level of genetic variation in its genome. Thus, a vaccine that can induce cross-reactive neutralization activities will be needed. Studies on the co-evolution of antibodies and viruses indicate that mimicking the natural infecti...

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Detalles Bibliográficos
Autores principales: Wan, Mingming, Yang, Xiao, Sun, Jie, Giorgi, Elena E., Ding, Xue, Zhou, Yan, Zhang, Yong, Su, Weiheng, Jiang, Chunlai, Shan, Yaming, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454455/
https://www.ncbi.nlm.nih.gov/pubmed/37628824
http://dx.doi.org/10.3390/ijms241612642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454455/
https://www.ncbi.nlm.nih.gov/pubmed/37628824
http://dx.doi.org/10.3390/ijms241612642

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