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Amyloids of α-Synuclein Promote Chemical Transformations of Neuronal Cell Metabolites

The assembly of α-synuclein into cross-β structured amyloid fibers results in Lewy body deposits and neuronal degeneration in Parkinson’s disease patients. As the cell environment is highly crowded, interactions between the formed amyloid fibers and a range of biomolecules can occur in cells. Althou...

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Detalles Bibliográficos
Autores principales: Horvath, Istvan, Mohamed, Khadra A., Kumar, Ranjeet, Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454467/
https://www.ncbi.nlm.nih.gov/pubmed/37629028
http://dx.doi.org/10.3390/ijms241612849