DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes

Epigenetic mechanisms can regulate how DNA is expressed independently of sequence and are known to be associated with various diseases. Among those epigenetic mechanisms, DNA methylation (DNAm) is influenced by genotype and the environment, making it an important molecular interface for studying dis...

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Detalles Bibliográficos
Autores principales: Xavier, Alexandre, Maltby, Vicki E., Ewing, Ewoud, Campagna, Maria Pia, Burnard, Sean M., Tegner, Jesper N., Slee, Mark, Butzkueven, Helmut, Kockum, Ingrid, Kular, Lara, Jokubaitis, Vilija G., Kilpatrick, Trevor, Alfredsson, Lars, Jagodic, Maja, Ponsonby, Anne-Louise, Taylor, Bruce V., Scott, Rodney J., Lea, Rodney A., Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454485/
https://www.ncbi.nlm.nih.gov/pubmed/37628757
http://dx.doi.org/10.3390/ijms241612576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454485/
https://www.ncbi.nlm.nih.gov/pubmed/37628757
http://dx.doi.org/10.3390/ijms241612576

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