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DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes
Epigenetic mechanisms can regulate how DNA is expressed independently of sequence and are known to be associated with various diseases. Among those epigenetic mechanisms, DNA methylation (DNAm) is influenced by genotype and the environment, making it an important molecular interface for studying dis...
Autores principales: | Xavier, Alexandre, Maltby, Vicki E., Ewing, Ewoud, Campagna, Maria Pia, Burnard, Sean M., Tegner, Jesper N., Slee, Mark, Butzkueven, Helmut, Kockum, Ingrid, Kular, Lara, Jokubaitis, Vilija G., Kilpatrick, Trevor, Alfredsson, Lars, Jagodic, Maja, Ponsonby, Anne-Louise, Taylor, Bruce V., Scott, Rodney J., Lea, Rodney A., Lechner-Scott, Jeannette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454485/ https://www.ncbi.nlm.nih.gov/pubmed/37628757 http://dx.doi.org/10.3390/ijms241612576 |
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