Elexacaftor Mediates the Rescue of F508del CFTR Functional Expression Interacting with MSD2

Cystic fibrosis (CF) is one of the most frequent lethal autosomal recessive diseases affecting the Caucasian population. It is caused by loss of function variants of the cystic fibrosis transmembrane conductance regulator (CFTR), a membrane protein located on the apical side of epithelial cells. The...

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Detalles Bibliográficos
Autores principales: Bongiorno, Roberta, Ludovico, Alessandra, Moran, Oscar, Baroni, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454486/
https://www.ncbi.nlm.nih.gov/pubmed/37629017
http://dx.doi.org/10.3390/ijms241612838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454486/
https://www.ncbi.nlm.nih.gov/pubmed/37629017
http://dx.doi.org/10.3390/ijms241612838

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