Pharmacological and Genetic Disruption of C-Type Natriuretic Peptide (nppcl) Expression in Zebrafish (Danio rerio) Causes Stunted Growth during Development

Human patients with mutations within NPPC or NPR2 genes (encoding C-type natriuretic peptide (CNP) and guanylyl cyclase-B (GC-B), respectively) display clinical signs associated with skeletal abnormalities, such as overgrowth or short stature. Mice with induced models of Nppc or Npr2 deletion displa...

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Detalles Bibliográficos
Autores principales: Lessey, Andrew J., Mirczuk, Samantha M., Chand, Annisa N., Kurrasch, Deborah M., Korbonits, Márta, Niessen, Stijn J. M., McArdle, Craig A., McGonnell, Imelda M., Fowkes, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454581/
https://www.ncbi.nlm.nih.gov/pubmed/37629102
http://dx.doi.org/10.3390/ijms241612921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454581/
https://www.ncbi.nlm.nih.gov/pubmed/37629102
http://dx.doi.org/10.3390/ijms241612921

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