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Mutations of BRCA1, BRCA2, and PALB2 Genes in Breast Tumor Tissue: Relationship with the Effectiveness of Neoadjuvant Chemotherapy and Disease Prognosis

It has been shown that the loss of function of the BRCA1, BRCA2, and PALB2 genes due to a number of hereditary mutations or chromosomal aberrations can affect the effectiveness of chemotherapy treatment and disease prognosis in patients with various types of cancer, and in particular in breast cance...

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Detalles Bibliográficos
Autores principales: Tsyganov, Matvey M., Sorokovikova, Sofia S., Lutzkaya, Elizaveta A., Ibragimova, Marina K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454606/
https://www.ncbi.nlm.nih.gov/pubmed/37628606
http://dx.doi.org/10.3390/genes14081554