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Insights into the Mechanism of Curaxin CBL0137 Epigenetic Activity: The Induction of DNA Demethylation and the Suppression of BET Family Proteins

The development of malignant tumors is caused by a complex combination of genetic mutations and epigenetic alterations, the latter of which are induced by either external environmental factors or signaling disruption following genetic mutations. Some types of cancer demonstrate a significant increas...

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Detalles Bibliográficos
Autores principales: Maksimova, Varvara, Popova, Valeriia, Prus, Anzhelika, Lylova, Evgeniya, Usalka, Olga, Sagitova, Guzel, Zhidkova, Ekaterina, Makus, Julia, Trapeznikova, Ekaterina, Belitsky, Gennady, Yakubovskaya, Marianna, Kirsanov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454690/
https://www.ncbi.nlm.nih.gov/pubmed/37629054
http://dx.doi.org/10.3390/ijms241612874