Inhibition of USP2 Enhances TRAIL-Mediated Cancer Cell Death through Downregulation of Survivin

Ubiquitin-specific protease 2 (USP2) is a deubiquitinase belonging to the USPs subfamily. USP2 has been known to display various biological effects including tumorigenesis and inflammation. Therefore, we aimed to examine the sensitization effect of USP2 in TRAIL-mediated apoptosis. The pharmacologic...

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Detalles Bibliográficos
Autores principales: Lee, Tak Gyeom, Woo, Seon Min, Seo, Seung Un, Kim, Shin, Park, Jong-Wook, Chang, Young-Chae, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454696/
https://www.ncbi.nlm.nih.gov/pubmed/37628997
http://dx.doi.org/10.3390/ijms241612816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454696/
https://www.ncbi.nlm.nih.gov/pubmed/37628997
http://dx.doi.org/10.3390/ijms241612816

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