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Impaired Repopulating Ability of Uhrf2(−/−) Hematopoietic Progenitor Cells in Mice

UHRF proteins catalyze the ubiquitination of target proteins and are involved in regulating gene expression. Some studies reported a reduced expression of UHRF2 in acute leukemia cells, but the role of UHRF2 in hematopoiesis remains unknown. Here, we generated Uhrf2(−/−) mice to clarify the role of...

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Detalles Bibliográficos
Autores principales: Sano, Takahiro, Ueda, Koki, Minakawa, Keiji, Mori, Tsutomu, Hashimoto, Yuko, Koseki, Haruhiko, Takeishi, Yasuchika, Ikeda, Kazuhiko, Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454722/
https://www.ncbi.nlm.nih.gov/pubmed/37628583
http://dx.doi.org/10.3390/genes14081531