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Further Developments towards a Minimal Potent Derivative of Human Relaxin-2

Human relaxin-2 (H2 relaxin) is a peptide hormone with potent vasodilatory and anti-fibrotic effects, which is of interest for the treatment of heart failure and fibrosis. H2 relaxin binds to the Relaxin Family Peptide Receptor 1 (RXFP1). Native H2 relaxin is a two-chain, three-disulfide-bond-contai...

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Detalles Bibliográficos
Autores principales: Handley, Thomas N. G., Praveen, Praveen, Tailhades, Julien, Wu, Hongkang, Bathgate, Ross A. D., Hossain, Mohammed Akhter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454739/
https://www.ncbi.nlm.nih.gov/pubmed/37628851
http://dx.doi.org/10.3390/ijms241612670