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The Molecular Mechanism of Positive Allosteric Modulation at the Dopamine D1 Receptor

The dopamine D1 receptor (D1R) is a promising target for treating various psychiatric disorders. While upregulation of D1R activity has shown potential in alleviating motor and cognitive symptoms, orthosteric agonists have limitations, restricting their clinical applications. However, the discovery...

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Detalles Bibliográficos
Autores principales: Goldberg, Alexander, Xie, Bing, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454769/
https://www.ncbi.nlm.nih.gov/pubmed/37629030
http://dx.doi.org/10.3390/ijms241612848