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Comparative Thrombin Generation in Animal Plasma: Sensitivity to Human Factor XIa and Tissue Factor

Preclinical evaluation of drugs in animals helps researchers to select potentially informative clinical laboratory markers for human trials. To assess the utility of animal thrombin generation (TG) assay, we studied the sensitivity of animal plasmas to triggers of TG, human Tissue Factor (TF), and A...

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Detalles Bibliográficos
Autores principales: Liang, Yideng, Tarandovskiy, Ivan, Surov, Stepan S., Ovanesov, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454801/
https://www.ncbi.nlm.nih.gov/pubmed/37629101
http://dx.doi.org/10.3390/ijms241612920