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A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths globally. Incidence rates are steadily increasing, creating an unmet need for new therapeutic options. Recently, the inhibition of sirtuin-2 (Sirt2) was proposed as a potential treatment for HCC, despite contradictory findi...

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Detalles Bibliográficos
Autores principales: Schmidt, Alexandra V., Monga, Satdarshan P., Prochownik, Edward V., Goetzman, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454864/
https://www.ncbi.nlm.nih.gov/pubmed/37628798
http://dx.doi.org/10.3390/ijms241612618