AMPK/FOXO3a Pathway Increases Activity and/or Expression of ATM, DNA-PKcs, Src, EGFR, PDK1, and SOD2 and Induces Radioresistance under Nutrient Starvation

Most solid tumors contain hypoxic and nutrient-deprived microenvironments. The cancer cells in these microenvironments have been reported to exhibit radioresistance. We have previously reported that nutrient starvation increases the expression and/or activity of ATM and DNA-PKcs, which are involved...

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Detalles Bibliográficos
Autores principales: Urushihara, Yusuke, Hashimoto, Takuma, Fujishima, Yohei, Hosoi, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454868/
https://www.ncbi.nlm.nih.gov/pubmed/37629008
http://dx.doi.org/10.3390/ijms241612828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454868/
https://www.ncbi.nlm.nih.gov/pubmed/37629008
http://dx.doi.org/10.3390/ijms241612828

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