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Osteoblast-Derived Matrix Vesicles Exhibit Exosomal Traits and a Unique Subset of microRNA: Their Caveolae-Dependent Endocytosis Results in Reduced Osteogenic Differentiation

Matrix vesicles (MVs) are nano-sized extracellular vesicles that are anchored in the extracellular matrix (ECM). In addition to playing a role in biomineralization, osteoblast-derived MVs were recently suggested to have regulatory duties. The aims of this study were to establish the characteristics...

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Detalles Bibliográficos
Autores principales: Skelton, Anne M., Cohen, D. Joshua, Boyan, Barbara D., Schwartz, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454939/
https://www.ncbi.nlm.nih.gov/pubmed/37628952
http://dx.doi.org/10.3390/ijms241612770