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Identification of hub ubiquitin ligase genes affecting Alzheimer’s disease by analyzing transcriptome data from multiple brain regions

The ubiquitin-proteasome system (UPS) plays crucial roles in numerous cellular functions. Dysfunction of the UPS shows certain correlations with the pathological changes in Alzheimer’s disease (AD). This study aimed to explore the different impairments of the UPS in multiple brain regions and identi...

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Detalles Bibliográficos
Autores principales: Liu, Dahai, Dai, Shao-Xing, He, Kan, Li, Gong-Hua, Liu, Justin, Liu, Leyna G, Huang, Jing-Fei, Xu, Lin, Li, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454942/
https://www.ncbi.nlm.nih.gov/pubmed/33754896
http://dx.doi.org/10.1177/00368504211001146