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Downregulation of Swine Leukocyte Antigen Expression Decreases the Strength of Xenogeneic Immune Responses towards Renal Proximal Tubular Epithelial Cells

Xenotransplantation reemerged as a promising alternative to conventional transplantation enlarging the available organ pool. However, success of xenotransplantation depends on the design and selection of specific genetic modifications and on the development of robust assays allowing for a precise as...

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Detalles Bibliográficos
Autores principales: Schmalkuche, Katharina, Schwinzer, Reinhard, Wenzel, Nadine, Valdivia, Emilio, Petersen, Björn, Blasczyk, Rainer, Figueiredo, Constanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454945/
https://www.ncbi.nlm.nih.gov/pubmed/37628892
http://dx.doi.org/10.3390/ijms241612711