Transcriptional Response to Standard AML Drugs Identifies Synergistic Combinations

Unlike genomic alterations, gene expression profiles have not been widely used to refine cancer therapies. We analyzed transcriptional changes in acute myeloid leukemia (AML) cell lines in response to standard first-line AML drugs cytarabine and daunorubicin by means of RNA sequencing. Those changes...

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Detalles Bibliográficos
Autores principales: More, Piyush, Ngaffo, Joëlle Aurelie Mekontso, Goedtel-Armbrust, Ute, Hähnel, Patricia S., Hartwig, Udo F., Kindler, Thomas, Wojnowski, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455220/
https://www.ncbi.nlm.nih.gov/pubmed/37629110
http://dx.doi.org/10.3390/ijms241612926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455220/
https://www.ncbi.nlm.nih.gov/pubmed/37629110
http://dx.doi.org/10.3390/ijms241612926

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