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PON-Fold: Prediction of Substitutions Affecting Protein Folding Rate
Most proteins fold into characteristic three-dimensional structures. The rate of folding and unfolding varies widely and can be affected by variations in proteins. We developed a novel machine-learning-based method for the prediction of the folding rate effects of amino acid substitutions in two-sta...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455311/ https://www.ncbi.nlm.nih.gov/pubmed/37629203 http://dx.doi.org/10.3390/ijms241613023 |