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PON-Fold: Prediction of Substitutions Affecting Protein Folding Rate

Most proteins fold into characteristic three-dimensional structures. The rate of folding and unfolding varies widely and can be affected by variations in proteins. We developed a novel machine-learning-based method for the prediction of the folding rate effects of amino acid substitutions in two-sta...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Chong, Zhang, Vihinen, Mauno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455311/
https://www.ncbi.nlm.nih.gov/pubmed/37629203
http://dx.doi.org/10.3390/ijms241613023